| Acronym | Definition |
|---|
| COB | Close Of Business (day) |
| COB | College of Business |
| COB | Coordination Of Benefits |
| COB | Children of Bodom (band; Finland) |
| COB | Chip On Board |
| COB | Commission des Operations de Bourse (French stock market regulator) |
| COB | Church of the Brethren |
| COB | Comitê Olímpico Brasileiro (Brazilian Olympic Committee) |
| COB | City of Bellingham (Washington) |
| COB | Conduct of Business |
| COB | Central Obrera Boliviana (Bolivian labor organization) |
| COB | City of Brownsville (Texas) |
| COB | Chairman of the Board |
| COB | College of the Bahamas |
| COB | California-Oregon Border |
| COB | Conan O'Brien (TV personality) |
| COB | Contingency Operating Base |
| COB | Country of Birth |
| COB | Chief Of the Boat |
| COB | COBOL Source Code (file name extension) |
| COB | Crew-Overboard |
| COB | Case of Beer |
| COB | Continuous Open Bidding (sorority/fraternity recruitment) |
| COB | Chris O'Brien (musician) |
| COB | Continuity of Business |
| COB | Capital One Bank |
| COB | Civilians on the Battlefield |
| COB | Carry on Business (license; India) |
| COB | City of Berkeley (California) |
| COB | Company of Biologists (Canada) |
| COB | Cost of Borrowing (loan financing) |
| COB | Colegio Oficial de Biólogos (Spanish: Association of Biologists) |
| COB | Class of Business |
| COB | Corn, Oats, & Barley (livestock feed) |
| COB | Center of Balance (measurement) |
| COB | Church Office Building (Church of Jesus Christ of Latter-day Saints) |
| COB | Center of Buoyancy (physics) |
| COB | Command Operating Budget |
| COB | Certificate of Birth |
| COB | Cost Of Business |
| COB | Chrome Over Brass (snare drums) |
| COB | Collocated Operating Base |
| COB | Continent Ocean Boundary |
| COB | Clothing Optional Beach |
| COB | City of Brass (game) |
| COB | Clean on Board (shipping) |
| COB | Circle of Bosses |
| COB | Clear-Over-Base (2-component car paints) |
| COB | Change of Basis (linear algebra, changing vectors from one basis to another) |
| COB | Commencement of Business |
| COB | City of Bridgetown (Barbados) |
| COB | Cranky Old Bastard |
| COB | Current on Board |
| COB | Contractors on the Battlefield |
| COB | Citizen Oversight Board |
| COB | Cut Out Background (digital photo manipulation) |
| COB | Cash on the Barrelhead |
| COB | Center for Oral Biology (Karolinska Institute; Huddinge, Sweden) |
| COB | Crusty Old Bastard |
| COB | Conformity Assessment Body |
| COB | Cargo Onboard |
| COB | Call On Business |
| COB | Council Of Brothers (gaming clan) |
| COB | Confirmation of Benefits (insurance) |
| COB | Communications Office Building (NASA) |
| COB | Cost of Billing |
| COB | Concluding Observation (United Nations) |
| COB | Continuously Overwhelmed with Blessings |
| COB | Combined Order of Battle |
| COB | Call Out Bonus |
| COB | CONUS Operating Base |
| COB | Commander of Brothers (gaming community) |
| COB | Coalition of Brothers (gaming community) |
| COB | Crotchety Old Bitch |