| Acronym | Definition |
|---|
| CASE | Computer-Aided Software Engineering |
| CASE | Council for Advancement and Support of Education |
| CASE | Center for Social and Economic Research (Poland) |
| CASE | Compressed Air System |
| CASE | Consumers Association of Singapore (nonprofit consumer protection agency) |
| CASE | Council of American Structural Engineers |
| CASE | Computer-Assisted Software Engineering |
| CASE | Cairo & Alexandria Stock Exchanges |
| CASE | Center for Architecture, Science and Ecology (Rensselaer Polytechnic Institute; New York) |
| CaSE | Campaign for Science and Engineering (UK) |
| CASE | Colorado Association of School Executives |
| CASE | Computer-Aided System Engineering |
| CASE | Citizenship and Service Education (Rutgers University) |
| CASE | Conference on Automation Science and Engineering (IEEE) |
| CASE | Computer Applications and Software Engineering |
| CASE | Conceptually Accurate Signed English |
| CASE | Carnegie Academy for Science Education |
| CASE | Cooperative Awards in Science and Engineering |
| CASE | Copy and Steal Everything |
| CASE | Computer Assisted Systems Engineering |
| CASE | Common Application Service Elements |
| CASE | Coatings, Adhesives, Sealants & Elastomers |
| CASE | Centrum Analiz Spoleczno-Ekonomicznych (Center for Social and Economic Research; Poland) |
| CASE | Canadian Association for Sound Ecology |
| CASE | Coalition Against Sexual Exploitation (various locations) |
| CASE | Chenega Advanced Solutions & Engineering, LLC |
| CASE | Coordinating Agency for Supplier Evaluation (industrial coalition; Hot Springs, AR) |
| CASE | Centre for Apologetic Scholarship and Education (New College, UNSW) |
| CASE | Club Athlétique de Saint-Étienne (French: Saint-Étienne Athletic Club; Saint-Étienne, France) |
| CASE | Campaign Against Stevenage Expansion |
| CaSE | Case Studies in Engineering Education |
| CASE | Coalition of Agencies Serving the Elderly |
| CASE | California Attorneys, Administrative Law Judges and Hearing Officers in State Employment (union) |
| CASE | Center for Aerospace Safety Education |
| CASE | Cellular Ammunition Storage Equipment (gaming) |
| CASE | Conformity Assessment System Evaluation |
| CASE | Coalition of American Structural Engineers |
| CASE | Center for the Advanced Study of the Environment |
| CASE | Counsel Automated Systems Environment |
| CASE | Copy and Share Everything |
| CASE | Collaborative Award in Science and Engineering (UK, ESRC) |
| CASE | Coordinated Air-Sea Experiment |
| CASE | Counselling Assistance to Small Enterprises (Canada) |
| CASE | Computer-Assisted Structural Engineering |
| CASE | Co-operative Awards in the Sciences of the Environment |
| CASE | Copy And Share with Everyone |
| CASE | Copy and Selectively Edit |
| CASE | Catholic Schools of Eau Claire (Eau Claire, Wisconsin) |
| CASE | Countywide Anti Substance-Abuse Efforts |
| CASE | Computer Automated Support Equipment |
| CASE | Corps Area Support Element |
| CASE | Cysteic Acid separating the dye and the SE |
| CASE | Controlled Airspace Synthetic Environment |
| CASE | Customer Application Support Engineer |
| CASE | Corps And Subordinate Echelons |
| CASE | Common Automated System Execution |
| CASE | Clean and Sober Experience |
| CASE | Community Awareness Safety Education |
| CASE | Combined Arms Synthetic Experiment |
| CASE | Computer Automated Software/System Engineering |
| CASE | Clemson Alumni Society for Equality |
| CASE | Customs-Approved Area for Storing Exports (New Zealand) |
| CASE | Caithness and Sutherland Enterprise (UK) |
| CASE | Circuits and Systems Exploration (Central Michigan University) |
| CASE | Centre d'Accueil Santé Échange (French: Home Health Exchange Center) |