| Acronym | Definition |
|---|
| CU | Copper (Cuprum) |
| CU | Credit Union |
| CU | Cubic |
| CU | See You (chat) |
| CU | Consumers Union (publisher of Consumer Reports) |
| CU | Cuba |
| CU | University of Colorado |
| CU | Close Up |
| CU | Close-Up |
| CU | Columbia University |
| CU | Cornell University |
| CU | Cambridge University |
| CU | Carleton University |
| CU | Coventry University (UK) |
| CU | Cover Up |
| CU | City University (main campus in Washington State) |
| CU | Clemson University |
| CU | Control Unit |
| CU | Colorado University |
| CU | Cumulus (cloud formation) |
| CU | Creighton University |
| CU | Concordia University |
| CU | Champaign-Urbana (Illinois) |
| CU | Commercial Union (insurance company) |
| CU | Carrie Underwood (singer) |
| CU | Christian Union |
| CU | Cairo University (Egypt) |
| CU | College Union |
| CU | Chinese University (Hong Kong) |
| CU | Cameron University |
| CU | Clarkson University (Potsdam, NY) |
| CU | Chapman University |
| CU | Cornerstone University |
| CU | Chulalongkorn University |
| CU | Cedarville University (Cedarville, OH) |
| CU | Colitis Ulcerosa (bowel disease) |
| CU | Customs Union (international trade relations) |
| CU | Cooper Union |
| CU | Clark University (Worcester, MA) |
| CU | cubic capacity (US DoD) |
| CU | Civil Union |
| CU | Central Unit |
| CU | Condensing Unit (HVAC) |
| CU | Campbell University |
| CU | Colgate University |
| CU | Common User |
| CU | Cultural Understanding |
| CU | Columbia Ultimate (collections software) |
| CU | Comenius University (Bratislava, Slovak Republic) |
| CU | Common Unit |
| CU | Channel Unit |
| CU | Communications Unit |
| CU | Calcutta University (India) |
| CU | Chronic Urticaria |
| CU | Crisp Uncirculated (paper currency grading) |
| CU | Combat Upgrade (Star Wars Galaxies, MMO gaming) |
| CU | Calibration Unit |
| CU | Celebrities Uncensored |
| CU | Century University |
| CU | Computer Unit |
| CU | Chittagong University |
| CU | Claflin University (Orangeburg, SC) |
| CU | Cheyney University |
| CU | Client Utility |
| CU | Configuration Update |
| CU | Cenhedloedd Unedig (Welsh: United Nations) |
| CU | Concord Law School (online law institution) |
| CU | Congressional Union (early suffragist movement) |
| CU | Crude Unit |
| CU | Combiner Unit |
| CU | Cattlemen's Union |
| CU | Customer Utilization |
| CU | Countermeasures Unit (for weapons of mass destruction; FBI) |
| CU | Correlated Uniqueness (statistical model) |
| CU | Column Uniform |
| CU | Cryptic Union (gaming) |
| CU | Close Utilization (forestry) |
| CU | Coefficient of Utilisation |
| CU | Cubana de Aviacion, SA Cuba (IATA airline code) |