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These two double-blind, placebo-controlled studies randomized 49 subjects with moderate-to-severe Crohn's disease as measured by the Crohn's Disease Activity Index (CDAI). In a Phase II study of PROCHYMAL for the treatment of patients with moderate to severe Crohn's Disease who had failed to respond to standard therapies, every patient evaluated experienced a reduction in Crohn's Disease Activity Index or PROCHYMAL is also being evaluated for the treatment of Crohn's Disease and has completed a Phase II trial, which demonstrated positive results, including a significant reduction in the Crohn's Disease Activity Index. |
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