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CTXB |
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The cholera toxin, encoded by the ctxA and ctxB genes, is the principal toxin produced by V. We amplified the ctxB gene using specific primers and found that the deduced amino acid sequence of the CT-B subunit of the Mozambique strains varied from the El Tor CT-B subunit at positions 39 (histidine replaces tyrosine in El Tor) and 68 (threonine replaces isoleucine in El Tor), and the amino acid residues at these positions are identical to those of the classical CTB subunit (Figure). |
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