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Cx43

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AcronymDefinition
Cx43Gap Junction Protein Connexin43 (gene)


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Gap junction remodeling and effect of Cx43 reduction According to current knowledge, gap junctions are considered to be crucial for the propagation of the cardiac impulse.
2001) found that Cx43 heterozygote null mice exhibited a significantly larger infarct volume compared to wild-type following focal ischemia.
In this study, the interaction between Cx43 (the major cardiac GJ protein) and ZO-1 in rat neonatal cardiomyocytes and HeLa cells was inhibited by a peptide designed to disrupt the binding of Cx43 and ZO-1.
 
 
 
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