d4T

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Acronym	Definition
d4T	Stavudine (aka Zerit; HIV treatment drug)
d4T	Didehydrodeoxythymidine (antiviral drug)

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References in periodicals archive ?

Among EFV-based regimens, adolescents on d4T + 3TC + EFV had higher odds of reporting multiple symptoms compared with those on TDF + FTC + EFV and ABC + 3TC + EFV (in that order of decreasing odds), suggesting that the NRTI backbone may play a more important role in cART symptoms profiling than the NNRTI component.

Beyond clinical trials: Cross-sectional associations of combination antiretroviral therapy with reports of multiple symptoms and non-adherence among adolescents in South Africa

A significantly higher proportion of patients on ARV regimen containing d4T reported adverse drug events compared to those on the other NRTI backbones.

Incidence and predictors of adverse drug events in an African cohort of HIV-infected adults treated with efavirenz

2] However, at the baseline visit, AZT was required to be substituted by d4T because of anemia (n = 6, 3.

A prospective study of highly active antiretroviral therapy in a tertiary-care hospital in south India

Lipoatrophy, which manifests as wasting of the buttocks, limbs and facial fat pads is caused by the NRTIs, particularly d4t, ddI and AZT.

Antiretroviral adverse drug reactions and their management: how to recognise, manage and avoid adverse effects of antiretrovirals

The instrument was set at 300, 285 and 270 nm for NVP, 3TC and d4T respectively.

Comparison of HPLC & spectrophotometric methods for estimation of antiretroviral drug content in pharmaceutical products

Two women died of PCP, and 2 of liver failure - 1 maternal death was presumed to be a result of complications from lactic acidosis following d4T toxicity.

Maternal outcomes following introduction of antiretroviral therapy in the public sector: a prospective study at a tertiary hospital in the Eastern Cape

In contrast, those who had been taking d4T showed better recovery of limb fat when they switched to TDF.

Nucleoside analogues in 2008

Krisana Kraisintu, director of the research-and-development institute at the Government Pharmaceutical Organization (GPO), said the institute took two and a half years to develop the formula for d4T, which will be marketed at 8 baht ($0.

Thailand begins manufacturing anti-AIDS drug d4T

Currently, Nelfinavir is resisted; changing two letters at RT 151 resists D4T, and changing one at PRO 90 resists Saquinavir.

Knowledge-Based Avoidance of Drug-Resistant HIV Mutants

As a result, the 2010 ARV guidelines focused on curbing morbidity and mortality associated with d4T and DDI.

Assessing adherence to the 2010 antiretroviral guidelines in the antiretroviral roll-out clinic at 1 Military Hospital, South Africa: a retrospective, cross-sectional study

Therefore, for those patients receiving stavudine (d4T), 3TC and EFV, switching to the FDC treatment can be considered as a single drug switch from d4T to TDF because 3TC and FTC are considered to be equivalent.

Fixed-dose combination for adults accessing antiretroviral therapy

75%) were resistant to 3TC and ABC; and 4/16 (25%) were resistant to d4T.

HIV-1 drug resistance genotypic profiles in children with undetectable plasma viremia during antiretroviral therapy