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DAPK1 |
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Gene expression profiling also distinguished underexpressed proapoptotic genes (ITPR3, 1GFBP3, and JUN), underexpressed tumor suppressors and growth inhibitors (FHIT, DAPK1, and MADH1), and overexpressed genes acting in cell cycle progression and in cell proliferation (CCNAI, BMYB, and CDKN3). In Celera's research studies, two single nucleotide polymorphisms (SNPs) were identified in DAPK1 that showed significant association with late-onset Alzheimer's disease in an analysis of up to six research sample sets with a total of 2,012 cases and 2,336 controls. |
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