| Acronym | Definition |
|---|
| DEP | Deputy |
| DEP | Deposit |
| DEP | Data Execution Prevention (computer security) |
| DEP | Department of Environmental Protection |
| DEP | Dependent |
| DEP | Departure |
| DEP | Depot |
| DEP | Deposition |
| DEP | deployed (US DoD) |
| DEP | Dillinger Escape Plan (band) |
| DEP | Diethyl Phthalate |
| DEP | Dielectrophoresis |
| DEP | Descanse En Paz (Spanish: Rest in Peace) |
| DEP | Direction de l'Education Permanente (French: Department of Further Education; est. 1974) |
| DEP | Débit Expiratoire de Pointe (French: peak expiratory flow) |
| DEP | Distributed Engineering Plant |
| DEP | Disability Education Program (Australia) |
| DEP | Displaced Employee Program |
| DEP | Data Entry Panel |
| DEP | Desert Eagle Pistol |
| DEP | Disability Equality Partnership (UK) |
| DEP | Design and Engineering Practice |
| DEP | Distal Embolic Protection (cardiology) |
| DEP | Disney's Electrical Parade |
| DEP | Droit de l'Environnement dans la Pratique (French) |
| DEP | Development Education Programme |
| DEP | Deaf Empowerment Program |
| DEP | Deflection Error Probable |
| DEP | Data Encryption Peripheral |
| DEP | Draft Equipment Publication |
| DEP | Defense Enterprise Program |
| DEP | Data Encryption Processor |
| DEP | Delayed Enlistment/Entry Program (US DoD) |
| DEP | Domestic Emergency Preparedness (FEMA) |
| DEP | Degressive Error Protection (algorithm) |
| DEP | Directory Enabled Provisioning |
| DEP | Division des Etudes et de la Prospective (French: Division of Studies and Forecasting) |
| DEP | Document Enterprise Platform |
| DEP | Distributed Engineering Plan |
| DEP | Dual Element Pump |
| DEP | Design External Pressure |
| DEP | Development and Environmental Project (Tanzania) |
| DEP | Descending Evoked Potential (neurophysiological intraoperative monitoring) |
| DEP | Dimanche de l'Eglise Persécutée (French: Sunday of the Persecuted Church) |
| DEP | Development Education Project |
| DEP | Disease Education Program (various organizations) |
| DEP | Division de l'Enseignement Privé (French: Division of Private Education) |
| DEP | Dipartimento de Economia Politica (Italian: Department of Economic Policy) |
| DEP | Depth-Of-Field Exposure Program (Canon) |
| DEP | Diagnostic Environnement Prévention (French: Environment Prevention Diagnostics) |
| DEP | Division des Établissements Privés (French: Private Institutions Division) |