DISCUSSION: This case study demonstrates that DMAB is highly toxic to humans through any route of exposure, and dermal absorption is the major route of neurotoxicity.
RELEVANCE: Further investigation of the toxic mechanism of DMAB is warranted.
DMAB is a white, crystalline solid with a molecular weight of 58.
Here we report a case of occupational DMAB exposure that caused significant neurotoxicity.
A 36-year-old, healthy male was accidentally sprayed over the face and trunk with the liquid form of DMAB (Figure 2).
DMAB was the only toxic substance at the workplace.
There were three other workers with a history of DMAB contamination.
To our knowledge, the human toxicity of DMAB has never been reported in the literature.
Delayed peripheral neuropathy was the second important presentation in this case of DMAB poisoning.
In a rat study, repeated administration of DMAB produced rather severe central nervous system lesions (BASF 2004).
Further research is needed regarding the mechanism of DMAB poisoning.