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DMSO |
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The content of eight defined individual polyaromatic hydrocarbons (PAH) cannot exceed 10 mg/kg, which is assumed to be met if the DMSO extractable amount in the oil is below 3% by method IP346. CPF was dissolved in dimethyl sulfoxide (DMSO), achieving final DMSO concentrations of 0. When the active ingredients were insoluble in water (nelfinavir and saquinavir), the contents were dissolved in dimethylsulphoxide (DMSO); care was taken to ensure that the final concentration of DMSO in the dilutions would not exceed 1%. |
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