DPNPDiabetic Peripheral Neuropathic Pain
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The setting of DPNP is one in which the concept of multimodal analgesia, or rational polypharmacy, frequently arises.
She was provided with education regarding DPNP, the benefits of treatment, and the importance of daily foot hygiene.
DPNP is a chronic pain condition that can be closely associated with mood disturbances.
The panel identify a number of gaps in available clinician information that need to be addressed to help improve both the understanding of DPNP and its effective assessment and management.
In two DPNP trials, controlled-release oxycodone significantly reduced all measures of pain.
Second-tier agents--with one randomized, controlled trial for DPNP and at least one trial in another painful neuropathy--include carbamazepine, gabapentin, lamotrigine, tramadol, and extended-release venlafaxine.
3Although all diabetics are at risk for DPNP, those most
Although it does not treat the underlying nerve damage caused by DPNP,
Physicians following the ASPE Consensus Guidelines for DPNP, with recently approved pharmacotherapies as recommended first-line treatment, may enable their patients to live a fuller, more independent life.
The Consensus Guidelines for DPNP, developed under an educational grant from Eli Lilly and Company, were jointly sponsored by the Johns Hopkins University School of Medicine and the American Society of Pain Educators.
Many DPNP patients have trouble enjoying family activities, and may even need to change jobs as a result of the pain.
Food and Drug Administration (FDA) approved Cymbalta in September 2004 as the first prescription drug proven to reduce DPNP in adults.