| Acronym | Definition |
|---|
| DPE | Digital Preservation Europe |
| DPE | Department of Public Enterprises (India) |
| DPE | Designated Pilot Examiner (conducts FAA checkrides) |
| DPE | Distributed Processing Environment |
| DPE | Dual-Phase Extraction (DNAPL removal system) |
| DPE | Downstream Promoter Element (nucleotide core promoter element) |
| DPE | Department of Physical Education (formerly Office of Physical Education; US Military Academy) |
| DPE | DELMIA Process Engineer |
| DPE | Data Processing Equipment |
| DPE | Dipivefrin (anti-glaucoma medicine) |
| DPE | Disk Processor Enclosure |
| DPE | Department of Postsecondary Education |
| DPE | Demilitarization Protective Ensemble |
| DPE | Developer and Platform Evangelist (Microsoft) |
| DPE | Device Provisioning Engine |
| DPE | Delivery Project Executive |
| DPE | Doctor of Physical Education |
| DPE | Double Piston Effect |
| DPE | Default Password Enumeration |
| DPE | Developing, Printing, Enlarging |
| DPE | Defensive Planning and Execution |
| DPE | Diffractive Phase Element |
| DPE | Digital Parametric Equalizer (electronic signal processing) |
| DPE | Dangerous Pile or Embankment (ground condition) |
| DPE | Decoupled Parameter Estimation |
| DPE | Data Processing Engineer |
| DPE | Dihydroxyphenylethanol |
| DPE | Direct Poverty Expenditure |
| DPE | Detroit Pony Express (band) |
| DPE | Digital Policy Environment |
| DPE | Document Processing Environment |
| DPE | Dye Penetrant Examination |
| DPE | Designated Plan Examiner |
| DPE | Diagnostic/Prescriptive/Evaluative |
| DPE | Dynamic Provisioning Environment |
| DPE | Dynamic Project Evaluation |