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Histological staging--bacterial depth of invasion Stage 1 * Superficial--bacteria on the surface * Eschar penetration--variable depth * Sub-eschar penetration and proliferation Stage 2 * Sub-eschar micro-invasion * Deep invasion into deeper tissues * Vascular and lymphatic involvement Table IV Profile of topical antimicrobials Agent Application frequency Eschar penetration Sodium hypochloride Daily for 20- Surface action NaOCl 0. Most of the literature advocating subdivision of the pT3 category has focused on rectal cancer, with the rationale of using the depth of invasion as a means of selecting patients for adjuvant therapy. 12) In a multifactorial analysis of the influence of sex, clinical stage, tumor thickness, and depth of invasion in 89 patients with buccal cancer, Urist et al found that the only independent prognostic factor was tumor thickness; tumors less than 6 mm thick were associated with an excellent prognosis (p < 0. |
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