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TGF alpha differentially expressed in liver foci induced by diethylnitrosamine initiation and peroxisome proliferator promotion. Comparisons of the knockout mouse liver tumor expression profiles with those induced by ciprofibrate or diethylnitrosamine showed that these mice shared a number of deregulated (up-or down-regulated) genes with ciprofibrate-induced liver tumors. Studies comparing repeated dosing for early postnatal, juvenile, adult time periods, or lifetime exposures exist for six mutagens [benzidine, diethylnitrosamine (DEN), 3-methylcholanthrene, safrole, urethane, and vinyl chloride; Tables 1, 2, 3; Supplementary Table S4 (http://ehp. |
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