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DHFR
(redirected from Dihydrofolate reductase)

   Also found in: Medical, Wikipedia 0.03 sec.
AcronymDefinition
DHFRDiHydroFolate Reductase
DHFRDirac-Hartree-Fock-Roothaan
DHFRDrustvo Hrvatskih Filmskih Redatelja (Croatian: Croatian Society of Film Directors)


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Recent work demonstrated that EGCG reduced dihydrofolate reductase activity, which would affect nucleic acid and protein synthesis.
Pemetrexed is an antifolate/antimetabolite with several molecular targets involved in both pyrimidine and purine neosynthesis: thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT).
Dihydrofolate reductase is required for the growth of actively dividing cells.
 
 
 
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