| Acronym | Definition |
|---|
| DRE | Direct Recording Electronic (electronic voting machine) |
| DRE | Department of Real Estate |
| DRE | Digital Rectal Examination |
| DRE | Drug Recognition Expert |
| DRE | Director of Religious Education |
| DRE | Direction Régionale de l'Equipement (French: Regional Directorate of Equipment) |
| DRE | Destruction and Removal Efficiency (measurement of number of molecules of a compound removed or destroyed in an incinerator) |
| DRE | Directors of Religious Education |
| DRE | Disk Read Error |
| DRE | Dynamic Reasoning Engine |
| DRE | Dense Rock Equivalent |
| DRE | Distributed Real-time and Embedded system |
| DRE | Defense Research and Engineering |
| DRE | Defence Research Establishment |
| DRE | Digital Radio Express (California) |
| DRE | diagnosis-related estimate |
| DRE | Doctor of Religious Education |
| DRE | Drummond Island, Michigan (Airport Code) |
| DRE | Data Reverse Engineering workshop |
| DRE | Directional Reservation Equipment |
| DRE | Design Responsible Engineer |
| DRE | Dilated Retinal Exam (tests for diabetic retinopathy) |
| DRE | Drug Resistant Epilepsy |
| DRE | Dead Reckoning Equipment |
| DRE | Ducted Rocket Engine |
| DRE | Defensive Right End (football) |
| DRE | Dead Reckoning Error |
| DRE | Delta Ray Edge (Mega Man Battle Network 3/4) |
| DRE | Diabetic Retinal Examination |
| DRE | Don Ron Entertainment |
| DRE | Directorate for Readiness |
| DRE | Door, Roll-Up, Electric |
| DRE | Detailed Report of Excavation |
| DRE | District Reserve Equipment |
| DRE | Director of Research and Engineering (Office of the Under Secretary of Defense for Acquisition) |
| DRE | Dunlop Renewable Energy Ltd (Kelowna, BC, Canada) |
| DRE | Delivering Race Equality (mental health) |
| DRE | Defect Removal Efficiency (quality metric) |