| Acronym | Definition |
|---|
| DRI | Direct Rendering Infrastructure (Unix/Linux graphics system) |
| DRI | Desert Research Institute |
| DRI | Defense Research Institute (organization for defense, insurance, and corporate counsel; Chicago, IL) |
| DRI | Direction des Relations Internationales (French: Delegation for International Relations) |
| DRI | Declarative Referential Integrity |
| DRI | Defense Reform Initiative |
| DRI | Death Row Inmate |
| DRI | Digital Research, Incorporated |
| DRI | Division des Relations Internationales (French: International Relations Division) |
| DRI | Data Resources, Incorporated |
| DRI | Denver Research Institute |
| DRI | Dynamic Response Index |
| DRI | Delco Remy International, Inc. (automotive components manufacturer) |
| DRI | Drilling Rate Index (engineering/geology) |
| DRI | Dead Reckoning Indicator |
| DRI | Disco Related Injury |
| DRI | Disability Rights Initiative |
| DRI | Data Ready Indicator |
| DRI | Digital Recording Interface |
| DRI | Decoder Reliability Information |
| DRI | Distributed Reconnaissance Infrastructure |
| DRI | Demon Research Initiative (Buffy the Vampire Slayer) |
| DRI | Date Required Inplace |
| DRI | Detailed Report of Investigation |
| DRI | Diploma in Radionuclide Imaging (College of Radiographers, UK) |
| DRI | Demand Reduction Initiative |
| DRI | Destination Routing Indicator |
| DRI | Designated Responsible Individual |
| DRI | Detection, Recognition, and Identification (Surveillance, Reconnaissance and Intelligence Systems) |
| DRI | Doncaster Royal Infirmary |
| DRI | Diamond Resorts International (various locations) |
| DRI | Directorate of Revenue Intelligence |
| DRI | Disaster Recovery Institute (Canada) |
| DRI | Digital Rights Ireland (civil rights) |
| DRI | Direct Relief International (Santa Barbara, CA) |
| DRI | Direct Reduced Iron |
| DRI | Dirty Rotten Imbeciles (band) |
| DRI | Development of Regional Impact |
| DRI | Diabetes Research Institute |
| DRI | Dietary Reference Intake |
| DRI | Differential Reinforcement of Incompatible Behaviors |
| DRI | Differential Rate of Interest |
| DRI | Disability Research Institute |
| DRI | Direct Reading Instrument (OSHA) |
| DRI | Digital Receiver Interface (OpenCable) |
| DRI | Diplomatic Readiness Initiative |
| DRI | Direct Renin Inhibitor |