| Acronym | Definition |
|---|
| DPE | Digital Preservation Europe |
| DPE | Department of Public Enterprises (India) |
| DPE | Designated Pilot Examiner (conducts FAA checkrides) |
| DPE | Distributed Processing Environment |
| DPE | Department of Physical Education (formerly Office of Physical Education; US Military Academy) |
| DPE | Dual-Phase Extraction (DNAPL removal system) |
| DPE | Direction des Personnels Enseignants (French: Management of Teaching Staff; various universities) |
| DPE | Delta Pi Epsilon (national honorary graduate society; est. 1936) |
| DPE | Downstream Promoter Element (nucleotide core promoter element) |
| DPE | Department of Postsecondary Education |
| DPE | Data Processing Equipment |
| DPE | Dipivefrin (anti-glaucoma medicine) |
| DPE | DELMIA Process Engineer |
| DPE | Disk Processor Enclosure |
| DPE | Delivery Project Executive |
| DPE | Developer and Platform Evangelist (Microsoft) |
| DPE | Demilitarization Protective Ensemble |
| DPE | Dynamic Performance Engineering (California) |
| DPE | Doctor of Physical Education |
| DPE | Device Provisioning Engine |
| DPE | Double Piston Effect |
| DPE | Default Password Enumeration |
| DPE | Developing, Printing, Enlarging |
| DPE | Defensive Planning and Execution |
| DPE | Digital Parametric Equalizer (electronic signal processing) |
| DPE | Diffractive Phase Element |
| DPE | Dihydroxyphenylethanol |
| DPE | Decoupled Parameter Estimation |
| DPE | Data Processing Engineer |
| DPE | Direct Poverty Expenditure |
| DPE | Detroit Pony Express (band) |
| DPE | Digital Policy Environment |
| DPE | Document Processing Environment |
| DPE | Dye Penetrant Examination |
| DPE | Distortion Product Emission |
| DPE | Designated Plan Examiner |
| DPE | Dangerous Pile or Embankment (ground condition) |
| DPE | Diagnostic/Prescriptive/Evaluative |
| DPE | Dynamic Provisioning Environment |
| DPE | Diagnostic de Performance Énergétique (French: Energy Performance Certificate) |
| DPE | Développement Post Embryonnaire (French: Post Embryonic Development) |
| DPE | Directorate of Primary Education (various locations) |
| DPE | Demonstrator in Physical Education (India) |
| DPE | Dynamisme Presse Édition (French: Dynamic Edition Press) |
| DPE | Diplômé par l'Etat (French degree) |
| DPE | Des Produits Efficaces (French: Efficient Products) |
| DPE | Division de la Police de l'Environnement (French: Police Division of the Environment; Belgium) |
| DPE | Dynamic Project Evaluation |
| DPE | Department of Planning and Economy (Abu Dhabi, United Arab Emirates) |
| DPE | DuPont Performance Elastomer |
| DPE | Division des Personnels Enseignants (French:Teaching Staff Division) |
| DPE | Direction de la Propreté et de l'Eau (French: Branch and Clean Water) |
| DPE | Disease Prevention Education |