| Acronym | Definition |
|---|
| DRC | Democratic Republic of Congo |
| DRC | Director(ate) of Reserve Components |
| DRC | Down (Stage) Right Center |
| DRC | Disability Resource Center |
| DRC | Disability Rights Commission (United Kingdom) |
| DRC | Department of Rehabilitation and Correction (Ohio, USA) |
| DRC | Disaster Recovery Center |
| DRC | Dynamics Research Corporation |
| DRC | Development Review Committee |
| DRC | Danish Refugee Council |
| DRC | Design Rule Checking |
| DRC | Dynamic Range Control (Dolby Digital) |
| DRC | Digital Reality Creation (Sony) |
| DRC | Design Rule Check |
| DRC | Domaine de La Romanee Conti |
| DRC | Desert Regional Center (Las Vegas, Nevada) |
| DRC | Dynamic Ride Control (Audi) |
| DRC | Dutch Reformed Church |
| DRC | Dolphin Research Center |
| DRC | D'ni Restoration Council (gaming, Myst Uru) |
| DRC | Disability Rights Center (Arkansas protection and advocacy system for those with disabilities) |
| DRC | Device Research Conference |
| DRC | Day Reporting Center (criminal justice) |
| DRC | Danish Red Cross |
| DRC | Detroit Rock City (movie) |
| DRC | Disability Rights Center of Kansas (formerly Kansas Advocacy & Protective Services) |
| DRC | Data Rate Control |
| DRC | Discrimination Research Center |
| DRC | Direct Responsible Charge |
| DRC | Drug Rehabilitation Center |
| DRC | Departmental Review Committee |
| DRC | Dispute Resolution Conference (court proceeding) |
| DRC | Data Review Committee |
| DRC | Delayed Retirement Credits (US Social Security Administration) |
| DRC | Dataram Corporation |
| DRC | Dual Resident Corporation |
| DRC | Data Reduction Center |
| DRC | Disaster Research Centre (USA) |
| DRC | Disclosure Review Committee |
| DRC | Democratic Representative Caucus (Canada) |
| DRC | Disney Reservation Center |
| DRC | Design Routing Code |
| DRC | Defense Review Committee |
| DRC | Digital Reference Centre (Athabasca University Library, Canada) |
| DRC | District Recruiting Command |
| DRC | Dartmouth Research & Consulting |
| DRC | Direct Reporting Command |
| DRC | Dinner Roll Call |
| DRC | Director of Resident Care |
| DRC | Digital Reality Crew (internet community) |
| DRC | Desmosedici Riders Club (French motorcycle club) |
| DRC | Départements et Régions Cyclables (French: Cyclable Departments and Regions) |
| DRC | Defense Research Committee |
| DRC | Design Rationale Capture |
| DRC | Direct Routed Call |
| DRC | Design Ready Controls (Minneapolis, MN) |
| DRC | Daily Readiness Check |
| DRC | Diablo Requiem Clan (gaming) |
| DRC | Deputy Regional Counsel (EPA) |
| DRC | Design Review Center |
| DRC | Data Record Control |
| DRC | Dalit Resource Centre (India) |
| DRC | Digitorenocerebral (syndrome) |
| DRC | Dynamic Rate Change |
| DRC | Data Re-Use Counter (Sprint) |
| DRC | Daily Record Card (clinical trials) |
| DRC | Doctoral Research Center (Institute for Transformative Thought and Learning; Arizona and California) |
| DRC | Deployment Readiness Condition |
| DRC | Data Relay Console |
| DRC | Disposal Release Confirmation |
| DRC | Disability Review Council |
| DRC | Data Routing Control |
| DRC | Dark Rum & Coke |
| DRC | Display Ready Case |
| DRC | Discoverer Recovery Capsule |
| DRC | Delhi Rail Corridor |
| DRC | Data Rate Clock (Symmerticom) |
| DRC | Distinctive Ringing Converter |
| DRC | Diverse-Redundant Component(s) |
| DRC | Dogbert's Ruling Class |
| DRC | Document Release Center |
| DRC | Destination Route Choice (Sprint) |
| DRC | Domain Resource Centre |
| DRC | Dammarie Rugby Club (Dammarie, France) |
| DRC | Documentation Retention Center |
| DRC | Designated Roth Contribution (retirement plans) |
| DRC | Dancing Robot Contest (Robot Battle tournament) |
| DRC | Deputy Regional Controller |
| DRC | Data Rights Clause |
| DRC | Default Rate Calculation (student financial aid) |
| DRC | Deschutes River Conservancy (Oregon) |
| DRC | Downtown Revitalization Committee (various locations) |
| DRC | Development Report Card (Corporation for Enterprise Development) |
| DRC | Dominique Rodgers-Cromartie (football player) |
| DRC | Digital Resource Commons (Ohio) |
| DRC | Development Resource Center (various locations) |