| Acronym | Definition |
|---|
| DME | Durable Medical Equipment |
| DME | Distance Measuring Equipment |
| DME | Diabetic Macular Edema |
| DME | Department of Minerals and Energy |
| DME | Distributed Management Environment |
| DME | Dimethoxyethane |
| DME | Digital Motor Electronics |
| DME | Dry Malt Extract |
| DME | Dimethylether |
| DME | Dubai Mercantile Exchange Limited |
| DME | Diploma in Mechanical Engineering |
| DME | Dakota Minnesota & Eastern (railroad) |
| DME | Dried Malt Extract |
| DME | Digital Media Edition (Microsoft) |
| DME | Diatomaceous Earth |
| DME | Department of Medical Education (Armed Forces Institute of Pathology) |
| DME | Decision Making Exercise |
| DME | Dropping Mercury Electrode |
| DME | Data Medium Exchange (SAP interface, bank transfers) |
| DME | Deputy Managing Editor |
| DME | Moscow, Russia - Domodedovo (Airport Code) |
| DME | Digital Media Exchange, Inc. (Philippines) |
| DME | Development, Modernization, and Enhancement |
| DME | Dell Media Experience |
| DME | Disturbance Monitoring Equipment (electrical grid operations) |
| DME | Direct Measurement Explorer |
| DME | Direct Machine Environment |
| DME | Deputy Medical Examiner |
| DME | Designated Medical Examiner (US FAA) |
| DME | Dynamic Modulus of Elasticity |
| DME | Dialogue, Music & Effects (from audio post-production, a type of deliverable mix) |
| DME | Domestic Marijuana Eradication Program |
| DME | Dmapedit (gaming map editor) |
| DME | Direct Marketing Expense |
| DME | Design Margin Evaluation |
| DME | Drive Motor Electronics |
| DME | Design Mission Effect |
| DME | Direct Manufacturing Expense |
| DME | Data Modulation Encoder |
| DME | Digital Mafia Enterprises, LLC |
| DME | Doctorate of Music Education |
| DME | Dielectric Midgap Energy Model |
| DME | Direction-Biased Motion Estimation |
| DME | Dependent Malic Enzyme |
| DME | Denis Mathez Entreprise (French construction company) |
| DME | Drinking Made Easy (TV show) |
| DME | Directed Molecular Evolution (method) |
| DME | Doby's Mill Elementary School (Lugoff, SC; also seen as DME) |
| DME | Distribution de Matériel Électrique (French: Electrical Equipment Distribution; Luxembourg) |
| DME | Dimier Marc Électricité (French electrical company) |
| DME | Dépannage Maintenance Électricité (French: Electrical Maintenance Troubleshooting) |
| DME | Distribution de Matériel Européen (French: European Equipment Distribution) |
| DME | Diploma in Metallurgy Engineering |