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9) The duration of therapy is not well determined and should be based on clinical and radiological improvement. 37) Multivariate analyses of data from the HIV Out-Patient Study (HOPS) cohort (23) indicate that the following are risk factors for lipoatrophy: exposure to and duration of thymidine analogs (particularly stavudine and zidovudine), age, CD4 T-cell count, viral load, duration of therapy in general, and White race. Likewise, the mean duration of therapy was significantly higher in the PTA group--3. |
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