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EEDD

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AcronymDefinition
EEDDEmployment and Earnings Data for Decision-Makers


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Large effects on permeation and/or block in sodium channels are caused by mutations of either the DEKA selectivity ring or the outer EEDD ring of negative charges (1-5,13,14,19,34-37).
The Orion 4000 IMUX modules also use Larscom's unique EEDD ("Enhanced Excessive Differential Delay") feature, which is currently deployed on Larscom's Orion 4000 NxE1 IMUX and has now been added to the NxT1 line.
A neighboring EEDD locus is known to influence permeation in Na channels but has not been included because it modifies conductance, not selectivity (110).
 
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