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The contents reflect the diversification of mutagenesis approaches that now include, besides classical gene targeting, methods such as gene modification by oligonucleotides, gene trap mutagenesis, RNAi-mediated knockdown, and ENU mutagenesis. The team used the mutagenic chemical ENU to generate hundreds of mutant zebrafish, from which they bred a line that did not respond to amphetamine administration (despite the presence of the drug in the fish's brain) but that appeared to be normal in all other ways. Finally, central nervous systems tumors appear highly dependent upon exposures to ENU and several other chemicals during appropriate developmental windows, particularly prenatally, as observed in several species including rat, mouse, and opossum (Jurgelski et al. |
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Entwicklungspolitik Online Entwicklungspolitischer Auftragsrahmen Entwicklungszusammenarbeit entwine entwine entwine entwine around entwined entwined entwinement entwinement entwinements entwinements entwines entwines entwining entwining entwist entwisted entwisting Entwistle Family History Association entwists Entwives Entwives Entwives Entymology Entymology Entymology entypy entypy ENU EnubilateEnubilous ENUCE enucleate enucleate enucleate enucleate enucleated enucleated enucleated enucleated enucleates enucleates enucleates enucleates enucleating enucleating enucleating enucleating enucleation enucleation enucleation enucleation enucleations enucleations enucleations enucleations enucleator enucleator enucleator | |||||
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