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55) Aspirin plus ER-DP reduced stroke risk by 23% over aspirin alone.
In progress now are trials validating ESPS2, comparing clopidogrel plus aspirin with aspirin alone, and comparing combination aspirin plus ER-DP with clopidogrel.
Until these trials are complete, reasonable first-line choices for secondary stroke prevention are aspirin alone or in combination with ER-DP.