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ERK1/2

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AcronymDefinition
ERK1/2Extracellular Signal-Regulated Kinases 1 and 2
ERK1/2Extracellularly-Regulated Kinase-1 and -2


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Goodman, (2000) ERK1/2 phosphorylation, induced by electromagnetic fields, diminishes during neoplastic transformation, J Cell Biochem, 78, 371-379.
At chronic time points, pharmacological manipulations of neuron-microglia and microglia-neuron signaling either through inhibition of microglial activation, inhibition of ERK1/2 phosphorylation, antagonism of PGE2 receptor binding, selective killing of microglia with Mac-1-SAP, and/or inhibition of CCL21 signaling all result in reduced pain phenotypes [10,12-13].
Furthermore, effects of thunberginols A and B on the expression of c-fos mRNA and on the phosphorylation of ERK1/2 and c-jun were examined to obtain information about their mechanism of action.
 
 
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