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A middle range for background pressure was selected because, although the volume of inspired air during spontaneous breathing has been shown to be higher during high background pressure than during low background pressure, high background pressure is known to lower end-expiratory lung volume ( nbsp;resistive loading, a surrogate for PLB, increased end-expiratory lung volume, and we related this to work by O'Donnell et al, (3) who noted similar findings. |
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