| Acronym | Definition |
|---|
| EPE | Editorial Projects in Education |
| EPE | Elvis Presley Enterprises |
| EPE | Empresa de Pesquisa Energética (Portuguese: Energy Research Company) |
| EPE | Extended Period of Eligibility |
| EPE | European Conference on Power Electronics and Applications |
| EPE | Expanded Polyethylene |
| EPE | Expected Positive Exposure (banking) |
| EPE | Estimated Position Error |
| EPE | Extraprostatic Extension |
| EPE | English Proficiency Exam |
| EPE | Enhanced Performance Engine |
| EPE | European Partners for Environment (Belgium) |
| EPE | Examinations for Professional Engineers |
| EPE | Electric Potential Energy |
| EPE | Enhanced Polyethylene (resin) |
| EPE | Everyday Productivity Education (Windows Vista) |
| EPE | Executives, Professionals and Entrepreneurs (market segment) |
| EPE | Employment Placement Enterprise |
| EPE | Energy and Process Engineering |
| EPE | Enhanced Privacy and Encryption |
| EPE | Elective Physical Education |
| EPE | Electronic Processing Equipment |
| EPE | Extrasolar Planets Encyclopaedia |
| EPE | Energetic Proton Events |
| EPE | Exit Pupil Expander |
| EPE | Enterprise and Platform Enabler (US DoD) |
| EPE | Experienced Programmer Education (IBM) |
| EPE | Enterprise & Platform Enabler |
| EPE | Expected Potential Exposure (banking) |
| EPE | Espaces Publics et Environnement (French: Environment and Public Spaces) |
| EPE | Ente Pubblico Economico (Italian: Economic Public Body) |