| Acronym | Definition |
|---|
| EDI | Electronic Data Interchange |
| EDI | Electron Drift Instrument (Cluster spacecraft) |
| EDI | Eidgenössisches Departement des Innern |
| EDI | Electronic Document Interchange |
| EDI | Electronic Data Interface |
| EDI | Electrodeionization (removal of ionized salts from water using electricity) |
| EDI | Echange de Données Informatisées (French: Electronic Data Interchange) |
| EDI | Education Development International (UK) |
| EDI | Extreme Deep Invader (fictional/movie aircraft) |
| EDI | Electronic Document Imaging |
| EDI | Edinburgh, Scotland, United Kingdom - Turnhouse (Airport Code) |
| EDI | Enterprise Development International |
| EDI | Executive Director, Inc. (Milwaukee, WI) |
| EDI | Extended Destination Index (register in x86 processors) |
| EDI | Edge-Directed Interpolation (image processing) |
| EDI | European Drug Index |
| EDI | ESQ Development Institute |
| EDI | Engineering, Design, and Inspection |
| EDI | Evaluate, Develop, Implement |
| EDI | Employee Development Inventory |
| EDI | European Defense Identity |
| EDI | Explain, Demonstrate, Imitate |
| EDI | Environmental Developers, Inc. |
| EDI | Economic Development Institute (Washington, DC) |
| EDI | Enterprise Development Initiative (various locations) |
| EDI | Ethereal Darkness Interactive (game) |
| EDI | Economic Development Initiative |
| EDI | Enhanced Defense Intelligence (Mass Effect; video game) |
| EDI | Eating Disorder Inventory |