| Acronym | Definition |
|---|
| EPO | Erythropoietin (endurance drug) |
| EPO | Emergency Power Off |
| EPO | Entwicklungspolitik Online |
| EPO | Education and Public Outreach (office) |
| EPO | Esperanto (ISO Language Code) |
| EPO | Eosinophil Peroxidase |
| EPO | Emergency Protective Order |
| EPO | Engineering Process Outsourcing |
| EPO | Emergency Preparedness Office |
| EPO | Enterprise Profit Optimization (Manugistics Group, Inc.) |
| EPO | Environmental Protection Order |
| EPO | Education Process Outsourcing |
| EPO | Electronic Purchase Order |
| EPO | Expanded Polyolefin (structural composites foam material) |
| EPO | Education Programs Office |
| EPO | Earthnet Programme Office |
| EPO | Enterprise Program Office (project management) |
| EPO | Employee Process Outsourcing |
| EPO | Elliniki Podosfairiki Omospondia (Greek Football Federation) |
| EPO | Etobicoke Philharmonic Orchestra |
| EPO | Environmental Protection Organization |
| EPO | Engineering Petty Officer (US Coast Guard) |
| EPO | Error Performance Objectives |
| EPO | Examination Procedure Outline |
| EPO | Estuarine Programs Office |
| EPO | European Philharmonic Orchestra |
| EPO | Enlisted Programs Officer (US DoD) |
| EPO | Electronic Philharmonic Orchestra |
| EPO | Eastern Philharmonic Orchestra |
| EPO | Engine Propeller Order |
| EPO | Equivalent Phase Object |
| EPO | End-Point-Object |
| EPO | Erie Philharmonic Orchestra |
| EPO | EOS Project Office |
| EPO | European Postman Organisation |
| EPO | European Patent Organisation |
| EPO | Evansville Philharmonic Orchestra |
| EPO | Environmental Protection Operations (Canada) |
| ePO | ePolicy Orchestrator (McAfee) |
| EPO | Epidemiology Program Office (US CDC) |
| EPO | European Patent Office |
| EPO | Exclusive Provider Organization |
| EPO | Evening Primrose Oil |