FADD


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AcronymDefinition
FADDForeign Animal Disease Diagnostician
FADDFAS-Associated via Death Domain (genetics)
FADDFathers Against Drunk Driving
FADDFriends against Drinking and Driving
FADDFighting Against the Digital Divide (University of North Carolina at Chapel Hill)
References in periodicals archive ?
Increased death receptor pathway of apoptotic signaling in septic mouse aorta: effect of systemic delivery of FADD siRNA.
Researchers found that mice that did not express FADD contained raised levels of RIP1, Receptor-Interacting Protein 1, an important protein that mediates necrosis and the apoptotic processes, and their embryonic development failed due to massive necrosis.
Se conoce que estas asociaciones reclutan moleculas adaptadoras como FADD (en ingles: Fas-Associated Death Domain) o TRADD (en ingles: TNF Receptor-Associated Death Domain), las cuales activan caspasas iniciadoras -8 y -10 y finalmente se da la activacion de caspasas ejecutoras -3, -6 y -7, lo que culmina en un fenotipo celular apoptotico con caracteristicas fisiologicas y morfologicas descritas en la tabla1 (Huerta et al.
This resistance is attributed to the binding of E6 with TNF receptor (TNFR) and thereby the inability of TNFR1 intracellular death domain to interact with FADD (29).
Ademas, la FADD tambien presenta otro dominio, denominado Dominio Efector de Muerte (DED, por sus siglas en ingles), y por interacciones homologas activa la procaspasa-8, la cual contiene un DED, se libera del Complejo de Senalizacion Inductor de Muerte (DISC; union de Fas, FasL, FADD y procaspasa-8) y en el citoplasma ejerce su actividad proteolitica sobre la caspasa-3, que es finalmente la molecula efectora (12-14,19) (ver figura 2).
The ratio of phosphorylated FADD to total FADD protein was significantly decreased at 30 minutes.
Esta forma de apoptosis se inicia cuando una celula blanco expresa un receptor de muerte celular como Fas, mientras que la celula efectora (celula NK en este caso) expresa el ligando denominado FasL; la interaccion de estas moleculas hace que la porcion intracelular de Fas se una a un factor adaptador intermediario denominado FADD (del ingles Fas-Associated Death Domain), interaccion molecular que lleva a la activacion de la via de las caspasas.
Tondu dished out some serious punishment at Whitland's expense, romping away to a 44-3 win at Pandy Park with props Kevin Fadd and Howell Davies among those who crossed for tries.
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
Some Early Definitions of the Tawriya and Safadi's Fadd al-Xitam an at-Tawriya wa-'l-Istixdam.
RT-PCR, which was performed to elucidate the effects of trifolin on the death receptor-mediated extrinsic apoptosis pathway, showed that concurrently, the mRNA levels of death receptors, including Fas and FADD, were increased (Fig.