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FOLFIRI

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AcronymDefinition
FOLFIRIFolinic Acid, Fluorouracil & Irinotecan (chemo treatment)


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Standard combination chemotherapy regimens comprising 5-fluorouracil (5-FU) plus leucovorin [LV, also known as folinic acid (FA)] in combination with irinotecan, typically FOLFIRI or oxaliplatin (FOLFOX) have been reported to facilitate the resection of 9%-40% of initially unresectable metastases [1, 2], with data emerging from randomized trials suggesting that the addition of targeted agents and a third cytotoxic might be even more effective.
K-RAS status and efficacy in the first-line treatment of patients with metastatic colorectal cancer (mCRC) treated with FOLFIRI with or without cetuximab: The CRYSTAL experience.
s tumor responded to treatment with FOLFIRI (folinic acid, 5-fluorouracil, and irinotecan) and bevacizumab but recently has progressed.
 
 
 
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