After incubation at 37[degrees]C for 1 hour, total and free apparent digoxin concentrations (in the protein-free ultrafiltrate prepared by centrifuging serum for 40 minutes at 1500g using Centrifree) were measured using the FPIA.
When the aliquots of drug-free serum pool were supplemented with Asian, American, and Indian ginsengs, significant apparent digoxin concentrations were observed using the FPIA (range, 0.
10]-methylpteroic acid; FPIA, fluorescence polarization immunoassay; LC-MS/MS, liquid chromatography-tandem mass spectrometry.
The method most commonly used for routinely measuring MTX in clinical laboratories is FPIA.
The company expects that R&D spending will continue to represent a larger percentage of sales while new FPIA
assays and associated laboratory instruments are under development.
Mean tHcy values obtained by the FPIA
method (n = 6) were significantly lower at low tHcy concentrations (7 [micro]mol/L) compared with values obtained by HPLC-FD using NaBH4/MBrB and TBP/SBDF as the reduction/ derivatization agents.
Lastly, heptaminol was added to drug-free urine specimens to determine the response of the AxSYM FPIA
assay for amphetamines.
To rule out the possibility that the observation of higher MEGX concentrations in uremic subjects was an artifact attributable to cross-reactivity with the TDx FPIA
by other lidocaine metabolites that may have accumulated in such patients, we compared the results of the FPIA
with those of a highly specific HPLC method in three healthy volunteers and three patients with severe renal dysfunction.
Digoxin-like immunoreactive substance: monoclonal and polyclonal RIA and FPIA
A tea was brewed from the leaves and analyzed by FPIA
after cooling to room temperature.