FSHDFlorida State Health Department
FSHDFacioscapulohumeral Muscular Dystrophy
FSHDFamily Studies and Human Development (degree program)
References in periodicals archive ?
a member of the Hutchinson Center's Human Biology Division, discovered that a rare variant of FSHD, called type 2, which accounts for about 5 percent of cases, is caused by two genetic mutations that together cause the production of muscle-damaging toxins responsible for causing symptoms of this progressive muscle disease.
Thus, there is ample opportunity for researchers to explore the experiences of individuals and families living with MG and other muscular dystrophies such as LGMD, FSHD, and OPMD.
But, he added, in a way FSHD was the easy case--it is a disease that affects every single person who inherits the genetic defect.
a member of the Hutchinson Center's Human Biology Division said that whether this is the sole cause of FSHD is not known; however, the latest findings "are about as strong of evidence as you can get" of the genetic link.
Both LGMD2B and FSHD are progressive, debilitating muscle diseases characterized by an immune component in the affected skeletal muscles.
In August 2010, an international team of researchers led by an investigator from Fred Hutchinson Cancer Research Center published a landmark study that established a new and unifying model for the cause of FSHD.
The Phase 1b/2 clinical trial in early onset FSHD is an international multi-center, open-label, intra-patient dose escalation study designed to assess the safety, tolerability, immunogenicity, and biological activity of Resolaris(TM).
They have identified a DNA sequence in individuals with FSHD that causes a gene called DUX4 to be more active.
Facioscapulohumeral muscular dystrophy, or FSHD, is the world's third most common type of muscular dystrophy.
Trials are planned in additional RMIC indications, including a study of patients with an early onset form of FSHD as well as an initial trial in rare pulmonary diseases with an immune component (RPIC) in patients with interstitial lung disease (ILD).