In 1997, Connolly et al (1) published a landmark study of valvular disease in patients who had taken the anorectic drug combination fenfluramine-phentermine (fen-phen).
Cases were selected by 2 criteria: the availability of AV and/or MV pathology material, and documented exposure to anorectic agents, including fenfluramine-phentermine in combination (fen-phen), fenfluramine alone, or dexfenfluramine alone.
Further cases of valvular heart disease associated with Fenfluramine-Phentermine [letter to the editor].
Fatal pulmonary hypertension associated with short term use of Fenfluramine-Phentermine.
John's wort as "herbal fenphen," intended to be an alternative to the anorectic combination therapy of fenfluramine-phentermine
In one study, 81 of the 121 subjects who originally took fenfluramine-phentermine
15 years ago were reevaluated by echocardiography, said Dr.
Looming larger for American Home Products are the suits concerning fenfluramine-phentermine
, the diet drug combination.
In the first study, 81 of the 121 subjects who originally took fenfluramine-phentermine
15 years ago in a study sponsored by the National Institutes of Health were tracked down and reevaluated by echocardiography, said Dr.