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FECH
(redirected from Ferrochelatase)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
AcronymDefinition
FECHferrochelatase
FECHFoundation Eye Care Himalaya (Nepal)


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This reduction in ferrochelatase activity frees protoporphyrin to accept zinc, resulting in the formation of zinc protophorphyrin, which is characteristically increased in both lead poisoning and iron deficiency.
Pb also interferes with the normal functioning of the intramitochondrial enzyme ferrochelatase, which is responsible for the chelation of iron by protoporphyrin.
We hypothesized that the different bioavailability of PbB determined by ALAD isotypes differentially affects ferrochelatase activity and therefore Hb synthesis.
 
 
 
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