(redirected from Flippase)
Also found in: Wikipedia.
FLPFamily Limited Partnership
FLPFollow Up
FLPFiji Labor Party
FLPFlippase (genetics)
FLPFast Link Pulse
FLPFront de Libération de la Palestine
FLPFasting Lipid Profile (lab test)
FLPFake Login Page (phishing technique)
FLPFeel Lucky Punk? (Quake2 gaming clan)
FLPFrançais Langue Professionnelle (French: French Language Education)
FLPFault Location Panel
FLPFlorida Light and Power
FLPFinancial Law Panel
FLPForklift Pockets
FLPForever Living Products LLC (Scottsdale, Arizona)
FLPFractional Load Planning
FLPFlying Laptop
FLPFlexible Precoding
FLPFunny-Looking Parent
FLPFestival Leisure Park (shopping centre in Basildon, Essex, England)
FLPFixed Log Periodical
FLPFinal Layer Painting
FLPFixed Logical Path
FLPFluorescent Panel
FLPFractional Linear Program
FLPFlippin, Arkansas, USA - Marion County Regional Airport
FLPFaith and Life Press (Newton, KS)
FLPFunny Looking Person
FLPFinancial Literacy Program (various organizations)
FLPFinishing Line Press (Georgetown, KY)
FLPFlow Line Pressure (petroleum industry)
FLPFamily Literacy Project (various locations)
References in periodicals archive ?
The PCR product was cloned to a BglII site upstream of the flippase recognition target (FRT) in pKD13 (20).
ATP8B1 encodes a P-type ATPase, FIC1, which is an aminophospholipid flippase that flips phosphatidylserine from the outer plasma leaflet of the canalicular membrane into the inner one.
It results from biallelic mutations in ABCB4 (7q21) encoding an ABC transporter, MDR3, which is a phospholipid flippase expressed in a variety of tissues.
Although a biochemical approach is an alternative, an assay for GlcN-PI flipping that is sufficiently sensitive to follow the purification of the flippase needs to be established for this approach to be feasible.
2+] inhibited flippase, an enzyme that recovers PS into the inner leaflet of the cell membrane, and activated scramblase, an enzyme that alters lipid asymmetry in the cell membrane.
6]-NBD-PS; Avanti Polar Lipids, Alabaster, AL, USA) for the flippase activity assay or 1-oleoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-sn-glycero-3-phosphocholine ([C.
6]-NBD-PC by flippase and scramblase, respectively, by comparing the fluorescence intensity associated with the cells before and after BSA back-extraction, as described in "Materials and Methods.
Increased intracellular calcium can mediate concomitant inhibition of flippase and activation of scramblase, leading to the disruption of membrane lipid asymmetry (Daleke 2003).
2+]-mediated thiol depletion was responsible for calcium increase--mediated and ATP depletion--mediated flippase inhibition and scramblase activation, leading to increased thrombin generation, enhanced adhesion of erythrocytes to endothelial cells, and ultimately, accelerated thrombus formation (Figure 6).
Moreover, depletion of free thiols in cells can cause depletion of ATP, inhibition of flippase (Daleke and Lyles 2000), and increased calcium, consistent with the result of the present study.
Next, enzyme flippases mediate transbilayer movement of the aforementioned intermediates to lumenal side of ER where conversion to [Glc.