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Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance.
14) It is a regulatory catalyst of anaerobic sugar metabolism (Embden-Meyerhof glycolytic and glucogenetic pathways) by reversibly converting glucose-6-phosphate to fructose-6-phosphate.
ATP, ADP, AMP, bis-[rho]NPP, [beta]-Glycerol phosphate, GTP, fructose-6-phosphate and PPi were used as substrates to determine the substrate specificity to the acid phosphatases activity, each one at a final concentration of 3.