| Acronym | Definition |
|---|
| FRS | Family Radio Service (US citizens band personal radio service) |
| FRS | Fisheries Research Services (Aberdeen, Scotland) |
| FRS | Financial Reporting Standard (UK Accounting Standards Board) |
| FRS | Florida Retirement System |
| FRS | File Replication Service (Microsoft Windows) |
| FRS | Fellow of the Royal Society |
| FRS | Fire and Rescue Service |
| FRS | Federal Relay Service |
| FRS | Facility Registry System (EPA) |
| FRS | Federal Reserve System |
| FRS | Foundation for Rural Service |
| FRS | Frame Relay Service |
| FRS | Financial Reporting System |
| FRS | Fleet Replacement Squadron |
| FRS | Flat Rate Scheme (UK) |
| FRS | Free Radical Scavenger (energy beverage) |
| FRS | Functional Rating Scale |
| FRS | Frame Relay Switch (Sprint) |
| FRS | Fire Research Station (UK) |
| FRS | Forward Repair System (US Army) |
| FRS | WordPerfect Graphics Driver (file name extension) |
| FRS | Fleet Readiness Squadron |
| FRS | Family Reconciliation Services |
| FRS | Face-Recognition Software |
| FRS | Freely Redistributable Software |
| FRS | Flores, Guatemala - Flores (Airport Code) |
| FRS | Firefighters' Retirement System |
| FRS | Flexible Route Selection |
| FRS | Filtered Rayleigh Scattering |
| FRS | Figure Rating Scale |
| FRS | Formal Reporting System |
| FRS | Force Républicaine de Sécurité (French: Republican Security Force; Madagascar) |
| FRS | Fax Recovery Systems, Inc |
| FRS | Ffestiniog Railway Society (Harbour Station, Porthmadog, Gwynedd, United Kingdom) |
| FRS | Frame Knowledge Representation System |
| FRS | Forward Recoil Scattering |
| FRS | Fluid Routing Solutions, Inc. |
| FRS | Fault Repair Signal |
| FRS | Feedback Research Services |
| FRS | Fundamental Reference System (ITU-T) |
| FRS | Functional Requirements Summary |
| FRS | Fleet Repair Service |
| FRS | First Repository States |
| FRS | Focus Rallye Sport |
| FRS | Financial Recovery Service, Inc. |
| FRS | First return stroke |
| FRS | Forward Repair Ship |
| FRS | Failure Reporting System |
| FRS | Factory Required Service |
| FRS | FOMIS Requirements Statement |
| FRS | Fully Responsive System |
| FRS | Family Rating Scale |
| FRS | Functional Requirements Specification |
| FRS | Foundation Routing and Switching (Cisco) |
| FRS | Faculty Research Seminar (various locations) |
| FRS | Frontier Research System (est. 1986; Japan) |