GABA-T

AcronymDefinition
GABA-TGlutamic Acid Decarboxylase and GABA Transaminase
References in periodicals archive ?
4) to assay GABA-T, it seemed to be worthwhile to optimize the assay conditions; formation of a different reaction product was measured ([[sup.
GABA-T ACTIVITY MEASUREMENTS IN LYSATES OF LYMPHOBLASTS AND LYMPHOCYTES
Vigabatrin ([gamma]-amino-5-hexenoic acid) is known to irreversibly inhibit GABA-T activity of bacterial origin (17).
EFFECT OF UNLABELED GABA AND [beta]ALA ON GABA-T ACTIVITY
To investigate the difference in affinity of GABA-T for both substrates, we incubated lymphoblast lysates with 400 nmol of [[sup.
We have developed a stable-isotope dilution method for measuring GABA-T activity in homogenates of lymphoblasts and lymphocytes.
N]][beta]ALA, by the enzyme GABA-T is an important finding in our work.
Finally, from the experiment with unlabeled substrates, we conclude that GABA-T has higher affinity for [[sup.
Among the flavonoids, baicalein was the most potent inhibitor of GABA-T with an [IC.
However, glycosylation of C-7 hydroxyl group did not change the order of SSADH inhibition as follows: scutellarein > baicalein and scutellarin > baicalin, differing from that of GABA-T inhibition.
1995) have reported that vigabatrin, a GABA-T inhibitor, may protect against kainic acid-induced neuronal damage.
GABA-T has been validated as an important target for neuroactive drugs.