GLURGlutamate Receptor
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GluRs are the predominant excitatory neurotransmitter receptors in the mammalian brain located primarily on the membranes of neuronal cells however recent findings have demonstrated expression of functional GluRs in non-neuronal peripheral cells such as skin, placenta, and colon.
GluRs are activated in a variety of normal neurophysiologic processes.
Metabotropic GluRs are powerful modulators of synaptic transmission in many brain regions, including the regulation of synaptic potentiation.