| Acronym | Definition |
|---|
| GSS | Generic Security Service |
| GSS | General Social Survey |
| GSS | Global Secure Systems |
| GSS | General Security Service |
| GSS | Global Site Selector (Cisco product used for name resolution and network routing) |
| GSS | Gerstmann–Straussler–Scheinker (medical condition) |
| GSS | Government Statistical Service (UK government) |
| GSS | Graduate Student Society |
| GSS | Group Support System (Visionquest) |
| GSS | Great Singapore Sale (Singapore) |
| GSS | Genome Survey Sequences |
| GSS | Glutathione Synthetase |
| GSS | Ground Support System |
| GSS | Guide to Safe Scouting |
| GSS | General Support System (US government) |
| GSS | Global Security Systems (Jackson, MS) |
| GSS | Gruppo di Studio della Scoliosi |
| GSS | General Support Services (Colorado) |
| GSS | Ground Soldier System |
| GSS | Gradjanski Savez Srbije (Serbian: Civil Union of Serbia; political party in Serbia-Yugoslavia) |
| GSS | Grouped Sweeping Scheduling (data placement algorithm) |
| GSS | Galileo Sistemas y Servicios (Spanish association) |
| GSS | Global Surveillance System |
| GSS | Gananoque Secondary School |
| GSS | Galileo Sensor Station |
| GSS | Generic Security Standard |
| GSS | Ground Surveillance Systems (GSR/REMBASS/IREMBASS) |
| GSS | Geodetic Survey Squadron |
| GSS | Geo-Stationary Satellite |
| GSS | Ground Station Simulator |
| GSS | Global Support System |
| GSS | General Security Support |
| GSS | General Service Schools |
| GSS | Global Shipping Software (US Postal Service) |
| GSS | Gate-Source Short (semi-conductors) |
| GSS | Gate Source Short |
| GSS | Game Support Specialist |
| GSS | Gilston State School (Gold Coast, Australia) |
| GSS | Generalized Stimulation Simulation |
| GSS | General Service Society |
| GSS | Grain and Salt Society |
| GSS | Generalized Spectral Shaping |
| GSS | Gyro Subsystem |
| GSS | Guidelines and Standards Subcommittee |
| GSS | Gichner Shelter System |
| GSS | Gerstmann-Straussier-Scheinker Syndrome (disease, transmissible spongiform encephalopathy) |
| GSS | Graphic Service System |
| GSS | Global Salmonella Survey (WHO) |
| GSS | Gaven State School (Gold Coast, Australia) |
| GSS | Guaranteed Share Scanner |
| GSS | Gravity Sensors System |
| GSS | General Supply Schedule |
| GSS | General Supply Support |
| GSS | General Servicing System (Bellcore) |
| GSS | GOES Sectorizer System |
| GSS | Global Synchronization Server |
| GSS | Gunster Student Center (University of Scranton) |
| GSS | Group Switch System |
| GSS | Generic Service Specification |
| GSS | Grey Sparling Solutions, Inc. |