| Acronym | Definition |
|---|
| GCS | Global Cooperation Society |
| GCS | Global Conceptual Schema |
| GCS | Geocentric Coordinate System |
| GCS | Guernsey Careers Service (UK) |
| GCS | Globe Clothing Store (California; est. 1995) |
| GCS | General Customer Survey |
| GCS | General Crane Service, Inc. |
| GCS | Gallager-Calderbank-Sloane (coding scheme) |
| GCS | geothermal circulation system |
| GCS | Gram-Charlier Series |
| GCS | Goodwill Cooperation Service (Seoul, Korea) |
| GCS | Gainesville Camellia Society (Florida) |
| GCS | Global Commodities and Services |
| GCS | Ground Control Site |
| GCS | Graded Compression Stocking |
| GCS | Guadalajara camptodactyly syndrome |
| GCS | Gilmore Community School (British Columbia) |
| GCS | Global Communication Server |
| GCS | Generalized Consecutive System |
| GCS | Gorn Confederate Ship (Star Trek) |
| GCS | Ground Control Surveillance |
| GCS | Ground Control Squadron |
| GCS | Glued Cylindrical Specimen |
| GCS | Ground Central Station |
| GCS | Ground Communications Segment |
| GCS | Ground Control Station |
| GCS | Glasgow Coma Scale |
| GCS | Global Cellular Service |
| GCS | Ground Control System |
| GCS | Group Communication Systems |
| GCS | Guidance Control System |
| GCS | Gun Computer System |
| GCS | Global Communications Solutions, Inc. (Fairport, NY) |
| GCS | Grand Central Station |
| GCS | Global Coordinate System |
| GCS | Glenelg Country School (Maryland) |
| GCS | Ground Combat Systems |
| GCS | Greene Climacteric Scale |
| GCS | Global CyberSoft |
| GCS | Global Corporate Services (company division) |
| GCS | Global Customer Support |
| GCS | Gift Card Solutions (Salt Lake City, UT) |
| GCS | Gastrointestinal Cancers Symposium |
| GCS | Global Civil Society (progressive politics) |
| GCS | Guidance Control Section |
| GCS | Ground Control Shelter |
| GCS | Genitourinary Cancers Symposium |
| GCS | Grilled Cheese Sandwich |
| GCS | General Conditions of Service |
| GCS | Guilford County Schools (North Carolina) |
| GCS | Ground Communications System |
| GCS | Gateway Computer System |