| Acronym | Definition |
|---|
| GEMS | Great Explorations in Math and Science |
| GEMS | Global Election Management System (Diebold) |
| GEMS | General Electric Medical Systems |
| GEMS | Global Enterprise Management Solutions |
| GEMS | Girls Health Enrichment Multi-Site Studies |
| GEMS | Global Enterprise Management System (AT&T) |
| GEMS | Global Emergency Management System (FEMA) |
| GEMS | Great Expectations in Math and Science |
| GEMS | Generic Error Modeling System |
| GEMS | Global Expeditionary Medical System (US DoD) |
| GEMS | Gulf Ecological Management Site |
| GEMS | Graphical Exposure Modeling System |
| GEMS | Global Enterprise Management of Storage |
| GEMS | Graphics Environment for Multimedia |
| GEMS | Ground Element MEECN System |
| GEMS | Giving Empowers My Sisters (Oshkosh, Wisconsin charitable group) |
| GEMS | Gaston Emergency Medical Services (Gaston County, North Carolina) |
| GEMS | Government Electronic Mail System |
| GEMS | Geographic Exploration and Mining Services (Ireland) |
| GEMS | Guidance Electronics Miniaturization and Structronics (DoD) |
| GEMS | General Energy Management System |
| GEMS | Generalized Energy Management Steering |
| GEMS | Government and Education Management Systems |
| GEMS | Graduate Education Management System |
| GEMS | Generic Establishment Management System |
| GEMS | Guide to ES&H Management Structure |
| GEMS | Gyrodata Electronic Magnetic Surveyor |
| GEMS | General Environmental Message Support |
| GEMS | Glockner Engineering & Mining Services (Australia) |
| GEMS | Global Emerging Market Sector (investing) |
| GEMS | Global Electronic Marketing Services |
| GEMS | Global Environment/al Monitoring System |
| GEMS | Galactic Emission Mapping |
| GEMS | Grouping Exponents Multiplication and division Subtraction and addition (Order Of Operations Pneumonic) |
| GEMS | Global Earth-System Monitoring with Satellite and In-Situ Data |