(redirected from Germinal Center B Cells)
GC-BGerminal Center B Cells
GC-BGuanylyl Cyclase Type B
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F, BCL2 immunohistochemical stain showing no expression by germinal center B cells (hematoxylin-eosin, original magnifications X20 [A and F] and X200 [B and C]; original magnifications X20 [D] and X200 [E]).
D, BCL6 immunohistochemical stain showing germinal center B cells displaced by inwardly migrating mantle zone B cells in 2 progressively transformed germinal centers.
4) One subgroup, termed germinal center B-cell-like (GCB) type, expresses genes characteristic of normal germinal center B cells.
BCL-6 is a transcription factor highly expressed in germinal center B cells but not in pregerminal B-cells, postgerminal memory cells, or plasma cells.
The germinal center B cells were positive in a cytoplasmic pattern in the dark zone.