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Abstract: Exenatide (synthetic exendin-4) is the analog of glucagon-like peptide 1 (GLP-1), the major physiologic incretin. Glucagon-like peptide 1 revs up and refurbishes insulin-making cells of the pancreas and might spawn the growth of new cells (164: 104). Improved glycaemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analogue liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial. |
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