| Acronym | Definition |
|---|
| GPI | Genuine Progress Indicator |
| GPI | Glucose-6-Phosphate Isomerase |
| GPI | Glycosyl Phosphatidylinositol |
| GPI | General Purpose Interface |
| GPI | Global Peace Index |
| GPI | General Purpose Input |
| GPI | Greenpeace International |
| GPI | Glass Packaging Institute |
| GPI | Glycophosphatidylinositol |
| GPI | Girls' Power Initiative (Nigeria) |
| GPI | Green Press Initiative |
| GPI | GOES Precipitation Index |
| GPI | General Pay Increase |
| GPI | Great Plains Industries, Inc (Wichita, Kansas) |
| GPI | General Paralysis of the Insane |
| GPI | Generic Product Identifier |
| GPI | Gas Puff Imaging |
| GPI | Ground Position Indicator |
| GPI | Grains Per Inch (arrow construction) |
| GPI | Glide Path Indicator (helipad lighting system) |
| GPI | Graphical Programming Interface |
| GPI | Global Partners Inc (Philippines) |
| GPI | Generalized Policy Iteration |
| GPI | Ground Point of Intercept |
| GPI | General Printing Ink |
| GPI | Global Precipitation Index |
| GPI | Groupement de Promotion Intégrale (French) |
| GPI | Gallons Per Inch |
| GPI | Government Preliminary Inspection |
| GPI | Ground Point Intercept |
| GPI | Generic Protocol Interface |
| GPI | Global Patent Information |
| GPI | Government Provided Information |
| GPI | Gerakan Pramuka Indonesia (Indonesian Scout Movement) |
| GPI | Global Positioning Instrument (aka GPS) |
| GPI | Global Procurement Information |
| GPI | Group Priority Inversion |
| GPI | Guide des Procédures de d’Immigration (Canada) |
| GPI | Group Presence Indicator |
| GPI | Gasket & Packings, Inc. (Borger, Texas) |
| GPI | Kalispell, Montana, USA - Glacier Park International Airport |
| GPI | Gordon Point Informatics Ltd. (Canada) |