HAP2Hook-Associated Protein 2
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The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes.
For example, the researchers found that HAP2, the gene that controlled whether cells fused, also is present in agriculturally important crops such as corn and wheat.
After realizing that the Plasmodium species, including the one that causes malaria in humans, also use "female" and "male" cells to reproduce, Snell found that blocking HAP2 in Plasmodium cells stops the fusing step.