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HGF/SF |
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ctn), the adaptor protein Gab 1, and the HGF/SF receptor Met. Binding of HGF/SF to c-MET activates downstream signalling pathways such as Rho, focal adhesion kinase (FAK) and PI3K. Data were also presented from a separate trial combining targeted therapies, in which AMG 102, a fully human monoclonal antibody that selectively targets HGF/SF (the only ligand for the c-Met receptor), was combined with bevacizumab or motesanib. |
HGF/SF |
HGDB HGDC HGDCIS hGDF3 HGDGF HGDH HGDI HGDK HGDM HGDN hGDNF HGDP HGDRE HGDS HGDSC HGDW HGE HGE HGE HGEA HGEC HGED HGEN HGET Hgf Hgf HGF-AF HGF/SF HGFAHGFAA hGFAP HGFC HGFD HGFF HGFFL HGFI HGfL HGFL/MSP HGFLP HGFM hGFP HGFR HGFS HGG HGGA HGGB HGGHH HGGM HGGP HGGR HGH HGH HGH HGH hGH-hPL | |||||
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