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HLA-DQ |
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Do particular HLA-DR or HLA-DQ alleles preferentially present peptides that elicit Th2-type cytokine production and promote allergic asthmatic conditions? Vandvik, now working in the transportation laboratory of the University of Oslo, decided to look at the relationships between MS and HLA-DQ. T-cell epitopes were identified, and transgenic mice with the HLA-DQ locus exhibited strong T-cell responses to short ragweed extracts. |
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